Epitranscriptomic regulation of sleep, neurodegeneration, and longevity
This research proposal investigates how a chemical modification called N6-methyladenosine (m6A) on messenger RNA influences brain health, specifically focusing on its role in sleep regulation, learning and memory, and neurodegenerative diseases such as Alzheimer’s.
Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Future Leaders in Canadian Brain Research
Province
Ontario
Start Date
2025
Phenotyping of Alzheimer’s disease across imaging-defined stages of cerebral amyloid angiopathy
Mixed dementia is the most common form of dementia.
Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Future Leaders in Canadian Brain Research
Province
Ontario
Start Date
2025
Trajectoires cérébrales normatives et atypiques : repenser le suivi du neurodéveloppement pédiatrique
Les commotions cérébrales chez les enfants sont un problème de santé publique majeur en raison de leur impact à long terme sur le développement cognitif et socio-émotionnel.
Grant type
Capacity building grants
Area of Research
Neurodevlopment
Competition
Future Leaders in Canadian Brain Research
Province
Québec
Start Date
2025
Identifying Proteogenomic Signatures Of Smoldering Lesions in Multiple Sclerosis
Multiple sclerosis (MS) is the most common cause of non-traumatic neurological disability, affecting 1 in 400 Canadian adults.
Grant type
Capacity building grants
Area of Research
Central Nervous System
Competition
Future Leaders in Canadian Brain Research
Province
Québec
Start Date
2025
Understanding cerebral blood flow control in humans after cannabis use
Cannabis is one of the most commonly used recreational substances in Canada, yet its effects on brain blood flow remain poorly understood.
Grant type
Capacity building grants
Area of Research
Central Nervous System
Competition
Future Leaders in Canadian Brain Research
Province
Ontario
Start Date
2025
New function for DEPTOR tyrosine 289 phosphorylation in glioma metabolism
Deregulation of brain cell metabolism is commonly observed in low-grade brain cancers.
Area of Research
Cancer
Competition
CRS Operating Grants
Province
Québec
Start Date
2025
Proteomic associations with brain and cognitive health and their interactions with modifiable risk factors for dementia
As people live longer, our society undergoes rapid demographic change.
Grant type
Capacity building grants
Area of Research
Neurodegeneration
Competition
Future Leaders in Canadian Brain Research
Province
Ontario
Start Date
2025
Dual-Actuated Acoustic Microbubble Microrobots for Targeted and Precision Brain Tumour Treatment
Glioblastoma is one of the most aggressive brain cancers, with very few treatment options and a poor survival rate.
Grant type
Capacity building grants
Area of Research
Cancer
Competition
Future Leaders in Canadian Brain Research
Province
Ontario
Start Date
2025
Defining and targeting clonal hematopoiesis as a driver of glioblastoma growth
We discovered that approximately one fifth of people with the deadly brain tumour glioblastoma show age-related genetic changes in their blood cells called ‘clonal hematopoiesis’, or CHIP.
Grant type
Team grants
Area of Research
Cancer
Competition
2025 Translational Research Grants in Brain Cancer
Province
Ontario
Start Date
2025
GPNMB CAR-T Cells as a Multi-Pronged Immunotherapeutic Approach for Glioblastoma
Glioblastoma (GBM) is the most common and deadly adult brain cancer.
Grant type
Team grants
Area of Research
Cancer
Competition
2025 Translational Research Grants in Brain Cancer
